The purpose of this experiment is to use hyaluronic acid, Vitamin E, silver nanoparticles, and a species specific bacteriophage cocktail to create a hydrogel. Unlike traditional hydrogels, which only aid in the protection and healing of wounds, this hydrogel would be able to heal wounds and burns by increasing cell proliferation while simultaneously disrupting biofilm formation and breaking down harmful bacteria strains that cause systemic nosocomial infections.
Hypothesis
If hyaluronic acid and Vitamin E are used in conjunction with colloidal silver and species specific bacteriophages, then cell proliferation in an in vitro wound healing model will increase.
Improving Wound Healing by Breaking Down Biofilm Formation and Reducing Nosocomial Infections 